USA Corporation Chromadex recently released a report regarding residual solvents and their risk when not properly monitored. For solvents, these are used to produce or are produced in the manufacture of drug substances, dietary ingredients or excipients and in the preparation of finished products, both pharmaceutical and dietary supplements.
Often these chemicals are not completely removed by the manufacturing processes utilized to produce finish products. Thus some level of residual solvents may be present in both the ingredients and finished products and their presence should be measured and justified.
ChromaDex states that despite clear requirements from a wide array of regulatory and compendia sources, it repeatedly finds that residual solvents testing is not adequately performed in the dietary supplement industry. ChromaDex’s work shows that a lack of residual solvent testing remains very common in the industry.
Risk assessments have been performed to determine tolerable daily intakes (TDI) and exposure limits of toxic chemicals by the International Program on Chemical Safety (IPCS). The World Health Organization and other national and international health authorities and institutes use acceptable daily intakes (ADI) for their guidelines.
ChromaDex report specifically addresses the current lack of attention to the identity and testing for residual solvents in ingredients and products within the Dietary Supplement industry.
As Tharos we remain fully committed to promote solvent-free supplements in particular and foods in general, preferably non-GMO, clean, traceable and completely safe to consume.
Full report at ChromaDex-Residual Solvents