Enhanced Cognitive Function and Antidepressant-Like Effects After Krill Oil Supplementation in Rats

After 7 weeks of krill oil (KO) intake, both males and females treated with KO were significantly better in discriminating between the active and the inactive levers in the ALSAT from day 1 of training . Both KO and IMIP prevented resignation/depression on the third day in the UALST. These data support a robust antidepressant-like potential and beneficial cognitive effect of KO.

Results indicate that active components (eicosapentaenoic acid EPA, docosahexaenoic acid DHA and astaxanthin) in KO facilitate learning processes and provide antidepressant-like effects. Findings also suggest that KO might work through different physiological mechanisms than IMIP.

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